The dynamic side of the Hofmeister effect: a single-molecule nanopore study of specific complex formation.

نویسندگان

  • Philip A Gurnev
  • Daniel Harries
  • V Adrian Parsegian
  • Sergey M Bezrukov
چکیده

Beyond measurements of equilibria: An alpha-hemolysin nanopore is used as a single-molecule sensor to follow the effects of different salts on the complexation reaction of gamma-cyclodextrin and adamantane carboxylate (see picture). The kinetics underlying the dynamic equilibrium are studied to reveal qualitatively different dynamic actions of various cosolute salts.

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عنوان ژورنال:
  • Chemphyschem : a European journal of chemical physics and physical chemistry

دوره 10 9-10  شماره 

صفحات  -

تاریخ انتشار 2009